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This is probably not an entire list of medicines which will interact with sildenafil. Always Verify with the Health care supplier.

†Irregular Vision: Gentle and transient, predominantly shade tinge to eyesight, and also enhanced sensitivity to light or blurred eyesight. In these scientific tests, just one affected person discontinued due to irregular eyesight.

The protection and efficacy of combos of VIAGRA with other PDE5 Inhibitors, together with REVATIO or other pulmonary arterial hypertension (PAH) treatment plans that contains sildenafil, or other solutions for erectile dysfunction have not been examined.

This metabolite features a PDE selectivity profile just like sildenafil and an in vitro potency for PDE5 about 50% with the mum or dad drug. Plasma concentrations of this metabolite are somewhere around forty% of People viewed for sildenafil, so the metabolite accounts for about 20% of sildenafil's pharmacologic consequences.

There have been extremely statistically important enhancements on the two principal IIEF queries (frequency of effective penetration during sexual exercise and routine maintenance of erections after penetration) on VIAGRA in comparison with placebo. On a global enhancement issue, 57% of VIAGRA individuals noted enhanced erections compared to ten% on placebo. Diary information indicated that on VIAGRA, forty eight% of intercourse attempts were being productive vs . twelve% on placebo.

In the four topics who gained VIAGRA one hundred mg in the initial component of the review, a extreme adverse event related to hypertension outcome was documented in a single affected individual (postural hypotension that began 35 minutes soon after dosing with VIAGRA with signs and symptoms lasting for eight hrs), and gentle adverse activities potentially associated with blood pressure consequences had been website claimed in two Other people (dizziness, headache and fatigue at one hour soon after dosing; and dizziness, lightheadedness and nausea at 4 several hours soon after dosing).

Doctors should really examine with clients the contraindication of VIAGRA with usage of guanylate cyclase stimulators for instance riociguat [see CONTRAINDICATIONS].

The following adverse reactions are already recognized through article acceptance use of VIAGRA. Simply because these reactions are described voluntarily from the populace of unsure dimension, It's not at all usually doable to reliably estimate their frequency or build a causal marriage to drug exposure.

At doses over the encouraged dose range, adverse reactions have been similar to All those in depth in Desk one underneath but frequently were noted a lot more regularly.

In the party of the erection that persists longer than 4 hrs, the individual must seek out instant medical support. If priapism is just not handled immediately, penile tissue problems and long lasting loss of potency may possibly final result [see WARNINGS AND Safety measures].

Hence, the metabolite is to blame for about 20% of sildenafil's motion. Sildenafil is excreted as metabolites predominantly while in the feces (about eighty% of administered oral dose) and to a lesser extent in the urine (all-around 13% of the administered oral dose). If taken having a large-Body fat meal, absorption is lowered; enough time taken to achieve the maximum plasma focus raises by about 1 hour, and the maximum concentration alone is lessened by almost one particular-3rd.[52]

Injection Liquid. Sildenafil injection is usually offered by a healthcare provider inside a healthcare facility or clinic. You won't retail outlet it in your house.

VIAGRA contains sildenafil, which is similar drugs located in An additional drug named REVATIO. REVATIO is employed to take care of a unusual disorder called pulmonary arterial hypertension (PAH).